痰瘀同治法治疗不稳定型心绞痛疗效的临床研究Clinical Study on Treating Unstable Angina Pectoris with Phlegm and Blood Stasis Tongzhi Therapy.pdfVIP

提 要 目的:通过对痰瘀同治法治疗不稳定型心绞痛的临床研究，探讨冠心病不稳定型 心绞痛新的治疗方法及疗效，探讨化痰祛瘀方治疗不稳定型心绞痛的机制，希望对中 医药在治疗不稳定型心绞痛方面有所帮助。 方法:将符合纳入标准的 50 例患者采取简单随机方法，分为治疗组 25 例和对照 组 25 例。对照组采用西药常规治疗；治疗组在西药常规治疗的基础上加服具有化痰 逐瘀，活血通脉功用的化痰祛瘀方，分别记录治疗前后心绞痛发作情况、中医症状的 变化情况、血压、心电图、血液流变学、血脂四项、一氧化氮(NO)、纤维蛋白原，高 敏C反应蛋白(hs–CRP) 等指标。 结果:临床观察表明，治疗组在改善患者临床症状，调脂、降低血液粘度和血小 板活化等方面均优于对照组(P0. 05)。 结论: 化痰祛瘀方是临床上治疗不稳定型心绞痛的一个服用安全、疗效确切的中 药复方制剂，具有明显的临床治疗作用，其能抗动脉粥样硬化形成、稳定动脉粥样斑 块，扩张冠状动脉、保护缺血心肌、改善心肌代谢，从而起到治疗心绞痛的作用。 关键词 痰瘀同治法；不稳定型心绞痛；胸痹心痛；化痰祛瘀方 The Study of Clinical research on Treating both Phlegm and Blood stasis in Treatment of Unstable Angina Pectoris Speciality：Internal Medicine of Traditional Chinese Medicine Author:Gao De zhen Tutor:Meng Zhao yang Abstract Objective: By treating both phlegm and blood stasis in the treatment of unstable angina pectoris clinical research, we hope to explore new treatments and the efficacy of unstable angina , and explore the mechanism of huatanquyu granule in the treatment of unstable angina pectoris.And we hope to have the help to traditional Chinese medicine in the treatment of unstable angina aspects. Methods: Divide the 50 patients who will meet the inclusion criteria into the treatment group 25 cases and control group 25 cases by simple random method. The control group use conventional treatment of Western medicine; The treatment group adds to the method that have the the function of Profiting qi, dispeling phlegm and promoting blood circulationon on the basis of the western medicine convention treatment foundation. Before and after the treatment record around separately the angina pectoris outbreak situation, the Chinese medicine symptom change situation, the blood pressure, the electrocardiogram, the blood r