维生素、FE复合酶含漱单一及联合治疗口腔溃疡复发的效果观察.docVIP

精品论文 参考文献 维生素、FE复合酶含漱单一及联合治疗口腔溃疡复发的效果观察 河南中医学院第三附属医院口腔科 450008 摘要：目的 研究维生素、FE复合酶含漱单一及联合治疗口腔溃疡复发的效果。方法 选取我院2012年3月-2013年7月94例口腔溃疡复发患者作为研究对象，抽签随机分为观察组与对照组，每组47例。观察组采取维生素＋FE复合酶含漱联合治疗，对照组采取FE复合酶含漱单一治疗。比较两组患者治疗有效率、治疗前后溃疡面积以及复发情况 结果 观察组总有效率93.6%、对照组78.7%，两组比较有统计学差异（p＜0.05）。观察组治疗后2d、5d溃疡面积分别为（2.01plusmn;1.83）mm2、（1.17plusmn;0.96）mm2，显著小于对照组的（5.16plusmn;3.35）mm2、（3.95plusmn;2.86）mm2，组间比较有统计学差异（p＜0.05）；观察六个月复发率，观察组19.1%、对照组63.8%，两组比较有统计学差异（p＜0.05）。结论 维生素、FE复合酶含漱联合治疗口腔溃疡复发的效果显著好于单一治疗。 关键词：维生素；FE复合酶含漱；口腔溃疡；联合治疗 Abstract：Objective To study the effects of vitamin，FE compound enzyme gargle alone and combined in the treatment of recurrent oral ulcer.Methods 94 patients with recurrent oral ulcer who were treated in our hospital between March 2012 and July 2013 were selected as the study object and were randomly divided into the observation group and the control group，with 47 cases in each group.The observation group were treated with vitamin combined with FE compound enzyme gargle while the control group were treated with FE compound enzyme gargle alone.The effective rate of treatment，ulcer area before and after treatment and recurrence in the two groups were compared.Results The total effective rate in the observation group was 93.6% while in the control group was 78.7%（P lt; 0.05）.On the 2nd and 5th day after treatment，ulcer areas of the observation group[（2.01plusmn;1.83）mm2，（1.17plusmn;0.96）mm2]were significantly smaller than those of the control group[（5.16plusmn;3.35）mm2，（3.95plusmn;2.86）mm2]（P lt; 0.05）；The 6-month recurrence rate was observed and that in the observation group was 19.1% while in the control group was 63.8%（P lt; 0.05）.ConclusionThe effects of vitamin combined with FE compound enzyme gargle in the treatment of recurrentoral ulcer are significantly better than those of single treatment. Key words：Vitamin；FE compound enzyme gargle；Oral ulcer；Combined therapy 口腔溃疡是常见的口腔疾病，此病发病率较高，有自愈性，但也极易复发。中医称之为“口疮”，多见于口唇、脸颊、舌头、软腭等部位，女性多于男性，发病率位于口腔黏膜疾病的第一位。大多数患者