AIDS Clinical Research英文资料.pdfVIP

AIDS Clinical Research Maina et al., J AIDS Clin Res 2014, 5:12 /10.4172/2155-6113.1000395 Review Article Open Access The Relative Balance between Th17 and Regulatory T cell subsets is Critical for Progression of HIV Infection 1,3 3 4 2 1 Maina EK , Bukusi EA , Martha S , Lartey M and Ampofo WK 1Virology Department, Noguchi Memorial Institute for Medical Research, Ghana 2University of Ghana, Medical School, Ghana 3Centre for Microbiology Research, Kenya Medical Research Institute, Kenya 4Malaria Program, Naval Medical Research Centre, USA * Corresponding author: Edward Maina, Virology Department, Noguchi Memorial Institute for Medical Research, P.O. Box LG 581 Accra, Ghana, Tel: 233265154115; E-mail: emaina02@ Received date: September 15, 2014; Accepted date: October 24, 2014; Published date: November 28, 2014 Copyright: © 2014 Maina EK, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Abstract HIV pathogenesis is extremely complex and involves both immunodeficiency that leads to opportunistic infections and AIDS as well as excessive inflammation and systemic immune activation. Generalized chronic immune activation and the progressive loss of the balance between T-helper 17 (Th17) and T-regulatory (Treg) cells have