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ITW 2004,San Antonio, Texas, October 24.29,2004
Information Theory and Coding Problems in Genetics
Olgica Milenkovicl and Bane Vasic
ECE Department, University of Colorado, Boulder, milenknvOschof.colorado.edu
Department of ECE/Mathematics, University of Arizona, Tucson, vasicOece.arizona.edu
Abstract: The aim of this paper is to describe a new class of relationship between spin glasses in statistical physics and
problems and some new results in coding theory arising from LDPC codes is an intensively studied topic [ l l , 141. In this
the analysis of the composition and functionality of the paper, we propose to extend this research area further, by
genetic code. The major goal of the proposed work is to showing that Boolean Networks (BN) used in biology and
initiate research on investigating possible connections dynamical systems theory, and inspired by statistical physics,
between the regulatory network of gene interactions (RNGI) contain LDPC codes as a special class of deterministic
and the proofreading (error-control) mechanism of the andlor random systems. We then proceed to propose some
processes of the central dogma of genetics. New results interdisciplinary problems regarding the nature of the
include establishing a direct relationship between Boolean proofreading mechanism of DNA replication and
Network (BN) Models of RNGI and Gallagers LDPC transcription. In this co
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