edited GTT2010(易晓芳)PPT.ppt

An increase in HCG (a doubling over a 2-week period) A plateau in HCG (decrease 10% per week) Once persistent GTD is diagnosed, chemotherapy is initiated unless complications, such as uterine hemorrhage or perforation, arise that require hysterectomy. This is important Quiz Discussion QUIZ 下列哪种情况需考虑GTD的可能性？ A. Persistent abnormal bleeding following normal pregnancy, abortion, or ectopic pregnancy. B. The finding of pulmonary nodules on chest radiograph after normal pregnancy. C. A young woman with an unknown primary neoplasm. D. A young woman with poorly explained hyperthyroidism. GTD最常继发于下列哪种情况？ A. Molar pregnancy B. Normal pregnancy C. Abortion D. Ectopic pregnancy. 监测和随访GTD时需检测下列哪个指标？ A. CA125 B. β-HCG C. AFP D. hPL 下列叙述哪些是正确的？ A. Partial moles are of paternal origin, are diploid, and carry a 20% risk of GTD sequelae. ? B. Complete moles are of maternal and paternal origin, are triploid, and rarely are followed by GTD. C. Partial moles require the same follow-up for potential malignant sequelae as a complete mole. D. The diagnosis of a molar pregnancy can be established with ultrasonography and may coexist with a normal pregnancy. ? 下列哪种方法处理葡萄胎最安全有效？ A. Hysterectomy B. Suction curettage C. Chemotherapy D. Radiotherapy 有关低危与高危型GTD的描述，下列哪些是正确的？ A. Low-risk categories receive single agent chemotherapy, usually methotrexate. B. High-risk patients receive combination chemotherapy, usually EMA/CO. ? C. Low-risk patients have a cure rate of less than 90%. D. Patients with high-risk metastatic GTD can not be treated. ? GTD的患者治疗结束后需避孕多长时间才能再怀孕？ A. 2 months. B. 6 to 12 months. ? C. 1 to 2 years. D. 3 to 5 years. (Doubilet P, Benson C: Atlas of Ultrasound and Obstetric Gynecology. Philadelphia, Lippincott Williams and Wilkins, 2003.) Case Review ??? What is the pathologic spectrum of disease associated with the entity in those patients with a positive serum β-hCG reading? Figure A, a sagittal image of the uterus, is from one pa