[医药卫生]Section A-Overview of the immune system.pptVIP

Role of stromal cells in hemopoiesis Fig 2 in page 13 (a) Stromal cell bound cytokine(e.g. stem cell factor) and (b) released cytokine(e.g. IL-7) determine the differentiation pathway of the stem cell(SC) (c) specific adhesion molecules(e.g. CD44) on the SC attached to hyaluronic acid molecules on the stromal cell. * * Immunolgy The role of cytokines Monocyte colony stimulating factor(M-CSF): development of monocyte Granulocyte colony stimulating factor(G-CSF): development of granulate * * Immunolgy 免疫学相关的诺贝尔奖获得者 About 30 scientists in 21 century became the Nobel laureates in physiology or medicine for works in immunology and related sister fields. 1901 E.A. Von Behring (Germany) for the work on serum therapy especially its application against diphtheria. 1905 R. Koch (Germany) for the investigations concerning tuberculosis. * * Immunolgy 1908 E. Metchnikoff (Russia) and P. Ehrlich (Germany) for their work on immunity (respectively, phagocytosis/cellular theory and humoral theory). 1913 C.R. Richet (France) for the work on anaphylaxis. 1919 J. Bordet (Belgium) for the discoveries relating to immunity (complement). 1930 K. Landsteiner (Austria/USA) for the discovery of human blood groups. * * Immunolgy 1951 M. Theiler (South Africa) for the discoveries and developments concerning yellow fever. 1957 D. Bovet (Italy/Switzerland) for the discoveries related to histamine and compounds, which inhibit action of histamine and other substances on the vascular system and the skeleton muscles. 1960 Sir F.McFarlane Burnet (Australia) and Sir P.B. Medawar (Great Britain) for the discovery of acquired immunological tolerance. 1972 G.M. Edelman (USA) and R.R. Porter (Great Britain) for their discovery concerning the chemical structure of antibodies. * * Immunolgy 1977 R. Yalow (USA) for the development of radioimmunoassays of peptide hormones. 1980 B. Benacerraf (USA), J. Dausset (France) and G.D. Snell (USA) for their discoveries concerning genetically determined