治疗肥胖促进糖尿病控制【精品课件】教材-课件.pptVIP

精神神經用藥與體重增加 抗抑鬱 (Anti-depressants) TCAs: ?amitriptyline ?imipramine MAOIs Nonselective Selective SSRIs Trazodone Lithium 抗精神病藥劑 (Anti-psychotics) Atypical 4 Phenothiazines 2-3 Haloperidol 1 Loxapine 0 (0 = lowest risk; 4 = highest risk) 抗癲癇藥劑 (Anti-epileptics ) Valproic acid 3-4 Carbamazepine 2 T-J WU 2-3 0 0 0 4 3 2 肥胖糖尿病人減重之困難 -25 -20 -15 -10 -5 0 Baseline 5 10 15 20 體重變化 百分比 (%) 週 數 糖尿病人 (n=12) 非糖尿病人 (n=12) -11.2% -20.2% p0.01 Wing RR et al. Diabetes Care 1987; 10: 563-6 T-J WU 減肥劑 (A