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Evidence based diuretics focus on chlorthalidone and…循证利尿剂集中在氯噻酮和.pdf
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Evidence-based diuretics: focus on
chlorthalidone and indapamide
,1 2 3,4
James J DiNicolantonio* , Jaikrit Bhutani , Carl J Lavie
James H O’Keefe1
ABSTRACT Thiazide and thiazide-like diuretics are cornerstone treatments for
hypertension. However, unlike chlorthalidone (CTD) and indapamide (IDP), hydro-
chlorothiazide (HCTZ) lacks evidence for reducing morbidity and mortality as monother
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