The MCM and RecQ Helicase Families Ancient Roles in DNA…和家族中的古代角色.pdfVIP

Chapter 3 The MCM and RecQ Helicase Families: Ancient Roles in DNA Replication and Genomic Stability Lead to Distinct Roles in Human Disease Dianne C. Daniel*, Ayuna V. Dagdanova and Edward M. Johnson Additional information is available at the end of the chapter /10.5772/52961 1. Introduction 1.1. Rationale for comparison of MCM and RecQ helicase families DNA helicases are currently organized into superfamilies based on their sequence structures and 3-D conformations. Within each supe