稳定性冠心病患者强化降脂精选.pptVIP

TNT: Treating to New Targets TNT: Design TNT: Baseline characteristics TNT: CV history of participants TNT: Baseline lipids TNT: 非心源性死亡率 TNT: 对治疗的耐受性 TNT: 降低LDL-C治疗的扩展的确切益处 已超越现有指南 * TNT: Treating to New Targets治疗达到新目标研究 TNT trial : New data on intensive lipid lowering in stable CHD patients 稳定性冠心病患者强化降脂 治疗的新数据 LaRosa JC et al. N Engl J Med. 2005;352. Hypothesis: Lowering LDL-C levels to well below 100 mg/dL could yield  an incremental clinical benefit Participants: 10,001 patients with stable CHD and LDL-C 130-250 mg/dL Treatments: Atorvastatin 10 mg and 80 mg Median follow-up: