(精选)医学课件内分泌生理教学课件.ppt

Chapter 11 ENDOCRINE PHYSIOLOGY内分泌生理 ;;I. Endocrine and hormone;1. Basic principles and organization;Distinction between these two communication systems —Nervous system and Endocrine system ;General definition for hormone;Living things that can secrete homones Multicelluar: Animal, Plant, Insect and Some fungi. Concentration Peptidal hormone in animal blood 10-12~10-10 M, Steroid hormone in animal blood 10-10~10-8 M. Endocrine cell and Target Cell, tissue and organ. Powerful Biological Effects Metabolic and Physiological effect. ; TABLE ENDOCRINE GLANDS, HORMONES SECRETED, AND TISSUE EFFECT ENDOCRINE GLAND HORMONES SECRETED TISSUE EFFECT Hypothalamus Corticotropin-releasing hormone (CRH) Stimulates ACTH secretion Dopamine Inhibits prolactin secretion Gonadotropin-releasing hormone (GnRH) Stimulates LH and FSH secretion Growth-hormone releasing hormone (GHRH) Stimulates GH secretion Somatostatin Inhibits GH secretion Thyrotropin-releasing hormone (TRH) Stimulates TSH and prolactin secretion Anterior Adrenocorticotropic hormone (ACTH) Stimulates synthesis/secretion pituitary of cortisol, androgens and aldosterone Follicle- stimulating hormone (FSH) Stimulates sperm maturation;