基本资料男n=83女n=69合计出生体重.docVIP

泸州市科技局科技计划项目（201110807） 泸医附院输血科 王华 0830-3165741 E-mail: 845936097@ 先天性梅毒临床流行病学调查分析 泸州医学院附属医院输血科 王华 张洪为 雷丽明 四川泸州 646000 【摘要】　目的　调查先天性梅毒患儿的临床流行病学资料，分析发病现状和发展趋势，为相关部门制定防控策略提供依据。 方法 采用回顾性分析方法，对本院2007-2011年收治的152例先天性梅毒患儿及其母亲临床诊疗资料进行流行病学统计分析。 结果　5年共收治先天性梅毒152例；2011年较2007年增长11.70倍；月龄以0~1月为主；患母85.5%为流动人口； 97.4%孕前未进行梅毒血清学筛查；88.8 %未予正规青霉素治疗。 结论　先天性梅毒严重影响新生儿的身体健康，其发生多见于农村流动人口，孕妇缺乏梅毒血清学筛查和正规青霉素治疗是导致先天梅毒发生的最主要因素，有关部门应加强对高危人群，尤其是农村流动人口的梅毒监控，大力宣传性病防治知识、产检以及梅毒早期治疗的重要性，提高公众医学和性道德素质。 【关键词】　先天梅毒 ； 流行病学；　新生儿 Clinical epidemiological investigation and analysis of congenital syphilis Wang Hua，Zhang Hong-wei，Lei Li-ming. Department of Blood Transfusion ，the Affiliated Hospital of Luzhou Medical college，luzhou 646000，China 【Abstract】　Objective Investigation the Clinical epidemiological material of congenital syphilis, and analysis the current situation and trend , in order to help government devise strategies.　Methods We tried to retrospectively analyze the history of pregnancy, the clinical manifestations, diagnosis and treatment of 152 congenital syphilis neonates from 2007 to 2011 in our hospital. Results　 152 congenital syphilis neonates were diagnosed in five years, and cases in 2011 were 11.7 times in 2007. Main cases were onset in less than 1 month. About 85.5% of the neoates’mothers were migrants who had poor education. About 97.4.0% of the mothers were lack of prenatal syphilis serologic testing ,and 88.8% of the mothers did not treated with appropriate penicillin regimen.　Conclusions　 Congenital syphilis seriously influences neonatal health, and it is more oftenly happened in immigrants. Lack of prenatal serologic testing and management of syphilis in immigrant pregnant women resulted in the accidence of congenital syphilis. Emphasis of government policy is adviced on supervision of syphilis among immigrants, and publicizes the significance on primary prevention of V.D. , antenatal examination and early therapy of syphilis. Besides the public，s medicine a