乳腺癌化疗患者癌性疲乏、应对方式与生活质量相关性.docVIP

乳腺癌化疗患者癌性疲乏、应对方式与生活质量相关性 　　【摘 要】 目的:探讨乳腺癌化疗患者癌性疲乏、应对方式与生活质量之间的相关性。方法:本研究是横断面研究,采用方便抽样法选择乳腺癌改良根治术后行药物化疗的女性患者120例,用癌性疲乏自评量表 (the Revised Piper Fatigue Scale,PFS)、Jalowiec的应对量表 (Jalowiec Coping Scale,JCS)和欧洲癌症研究与治疗组织开发的癌症患者生命质量测定系列量表的核心问卷[Quality of Life Questionnaire-Core 30,QLQ-C30(V3.0)]和针对乳腺癌人群的特异性问卷 (Quality of Life Questionnaire-Breast 23,QLQ-BR23),分别测评患者的癌性疲乏水平、应对方式和生活质量状况。采用Spearman相关分析患者癌性疲乏状况、应对方式以及生活质量三者之间的相关性。结果:乳腺癌化疗患者的癌性疲乏总分与QLQ-C30的功能和总体健康状况呈负相关(r=-0.24,-0.39;均P 　　【关键词】 癌性疲乏;乳腺癌化疗患者;应对方式;生活质量;相关研究 　　中图分类号:R746.9,R737.9 文献标识码:A 文章编号:1000-6729(2009)011-0776-05 　　 　　doi:10.3969/j.issn.1000-6729.2009.11.省略 　　【Abstract】 Objective:To explore the relationship among the cancer-related fatigue,coping styles and quality of life in breast cancer patients with chemotherapy.Methods:A total 120 female breast cancer patients were selected as the subjects.The instrument used for data collection was a questionnaire that was composed of four parts:the demographic data form,the Revised Piper Fatigue Scale (PFS),Jalowiec Coping Scale (JCS),Quality of Life Questionnaire-Core 30 (QLQ-C30),and Quality of Life Questionnaire-Breast 23 (QLQ-BR23).The statistical software SPSSwas used for data analysis.Cancer-related fatigue,coping styles,quality of life and their related factors were determined by nonparametric tests.Spearman correlation coefficient was used to investigate the relationship among cancer-related fatigue,coping styles and quality of life in breast cancer patients with chemotherapy.Results:There was a significant negative moderate correlation between cancer-related fatigue and the quality of life (r=-0.24,P 　　【Key words】 cancer-related fatigue;breast cancer patient with chemotherapy;coping style;quality of life;correlational study 　　 　　乳腺癌是女性最常见的恶性肿瘤之一,是女性癌症死亡的第二大原因 [1]。乳腺癌的综合性治疗给患者带来了各种负面的影响,而癌性疲乏是与癌症和癌症治疗有关的持续性、主观性疲倦劳累体验,它受生物节律的影响,可以在持续时间、不适感、强度上不断发生变化,它是癌症和癌症治疗中最常见的导致患者不适的症状。这种疲乏不能够通过休息得到彻底的缓解,严重影响患者的生活质量和自理能力[2-4],但目前它仍未引起患者甚至是医务工作人员的重视。新的生物-心理-