体检人群非酒精性脂肪性肝病患病率及相关因素分析.docVIP

体检人群非酒精性脂肪性肝病患病率及相关因素分析 　　【摘要】 目的：探讨鄄城县企事业单位非酒精性脂肪性肝病的患病率及其相关因素，以期为早期干预及改善NAFLD预后提供依据。方法：以参与健康体检的3102例人群为研究对象，收集相关体检资料进行统计学分析。结果：3102例中NAFLD的检出率为11.03%，经单因素和logistic多元回归分析，以甘油三酯、体重指数、空腹血糖、胆固醇、腰围、舒张压与NAFLD密切相关，其中甘油三酯、体重指数相对风险度最高（OR分别为1.637和1.357）。结论：本县区企事业单位NAFLD患病率较发达地区偏低，与肥胖、高血压、高脂血症、高血糖、年龄等代谢相关性疾病有关。 　　【关键词】 非酒精性脂肪性肝病； 流行现状； 相关因素 　　Analysis of Prevalence Rate and Related Factors of Nonalcoholic Fatty Liver Disease among the Physical Examination Crowd/ZHANG Jian-hua， LIU Xue-hua.//Medical Innovation of China，2014，11（01）：150-151 　　【Abstract】 Objective： To explore the contracting state and factors relating to nonalcoholic fatty liver（NAFL） among the people who are woke in the enterprise and business unit of Juancheng county， in relation to a period of early intervention and provide the basis for improving the prognosis of NAFLD. Method： The healthy physical examination results of 3102 cases were collected for statistical analysis. Result： The NAFLD detection rate in the 3102 cases was 11.03%. By univariate and multivariate logistic regression analysis to triglycerides， body mass index， fasting blood glucose， cholesterol， waist circumference， diastolic blood pressure was closely related with NAFLD， including triglycerides， body mass index highest relative risk （The OR was 1.637 and 1.35， respectively）. Conclusion： The morbidity rate of NAFL in the county is lower than the developed regions. The factors relating to NAFL are obesity， hypertension， hyperlipidemia， hyperglycemia， age and other metabolic related diseases. 　　【Key words】 Nonalcoholic fatty liver disease； Prevalence； Related factors 　　First-author’s address： Juancheng County People’s Hospital， Juancheng 274600， China 　　doi：10.3969/j.issn.1674-4985.2014.01.071 　　非酒精性脂肪性肝病（nonalcoholic fatty liver disease， NAFLD）是一种与胰岛素抵和遗传易感密切相关的代谢应激性肝脏损伤，疾病谱包括非酒精性单纯性脂肪肝、非酒精性脂肪性肝炎及其相关肝硬化和肝细胞癌。如能早期发现，并能及时对相关因素进行干预，多数可以治愈。但本病起病缓慢、隐匿，病程漫长，早期无明显临床症状，因此探讨NAFLD的相关危险因素对本病的早期诊断和防治具有重要临床意义。本文对在本院体检的企事业单位职工NAFLD的患病率及相关因素进行流行病学调