氟哌噻吨美利曲辛治疗慢性胃炎临床疗效观察.docVIP

氟哌噻吨美利曲辛治疗慢性胃炎临床疗效观察 　　doi：10.3969/j.issn.1007-614x.2014.14.18 　　摘 要 目的：探讨氟哌噻吨美利曲辛治疗慢性胃炎的临床疗效。方法：收治慢性胃炎伴轻中度抑郁焦虑的患者80例，随机分为两组。对照组采用常规消化内科治疗；治疗组采用常规消化内科治疗+氟哌噻吨美利曲辛片（黛力新），1片/日。治疗4周分别评价疗效。结果：氟哌噻吨美利曲辛治疗组临床疗效优于对照组，且精神症状明显改善。结论：氟哌噻吨美利曲辛可通过改善焦虑抑郁症状，提高慢性胃炎的治疗效果。 　　关键词 氟哌噻吨美利曲辛 慢性胃炎 抑郁焦虑 　　Observation of the clinical curative effect of Flupentixol and Melitracen Tablets in the treatment of chronic gastritis 　　Chen Jicheng 　　Xuchang Geology hospital of Henan Province，461000 　　Abstract Objective：To explore the clinical curative effect of Flupentixol and Melitracen Tablets in the treatment of chronic gastritis.Methods：We selected 80 cases of chronic gastritis with mild to moderate depression and anxiety of patients.These patients were randomly divided into two groups.The control group was treated with conventional treatment of Digestive System Department.The treatment group was treated with conventional treatment of Digestive System Department plus Flupentixol and melitracen tablets（Dai Lixin），1 tablet/day.Efficacy of the two groups was evaluated at 4 weeks after treatment.Results：The clinical curative effect of Flupentixol and Melitracen Tablets in the treatment of chronic gastritis was better than that of the control group，and the mental symptoms were improved remarkably.Conclusion：Flupentixol and Melitracen Tablets can improve the therapeutic effect of chronic gastritis by improving the symptoms of anxiety and depression. 　　Key words Flupentixol and Melitracen Tablets；Chronic gastritis；Depression and anxiety 　　慢性胃炎是临床中最常见的一种疾病，它对人们的健康和生活产生严重的影响，增加社会和家庭的负担。在以往的治疗中，慢性胃炎常不能彻底治疗，患者时有反复。在本研究中，我们收治慢性胃炎伴抑郁焦虑患者80例，分别采用常规消化内科治疗和常规消化内科治疗+氟哌噻吨美利曲辛片治疗，比较两组的治疗效果，现报告如下。 　　资料与方法 　　2012年12月-2013年12月收治慢性胃炎患者80例，男38例，女42例，年龄32～65岁，平均（46.3±10.5）岁。临床症状：上腹不适、上腹胀、早饱、嗳气、恶心等消化不良症状合并有失眠、焦虑情绪。所有病例均行胃镜检查，其中慢性非萎缩性胃炎48例，萎缩性胃炎26例，特殊性胃炎6例。随机分为对照组和治疗组，各40例，两组年龄、性别、病情等一般情况比较，差异无统计学意义（P0.05），具有可比性。 　　纳入标准：①对慢性胃炎的诊断标准，参照的是2006年中华医学会消化病学分会在上海制定的全国慢性胃炎共识。②对患者的精神状态评估，使用综合医院焦虑/抑郁（HAD）情绪测定表，且未服用过其他抗焦虑、抗抑郁药物[1]。