水源性感染述评20130530_副本.docVIP

医院水源性感染及预防和控制 周昭彦1　高晓东2 胡必杰2* 摘 要 水是医院感染中最重要、可控，又是最易被忽视的感染来源。研究表明，25%医院相关感染由水源性致病菌引起，14%-50%ICU病人感染和定植的铜绿假单胞菌与自来水分离株具有同源性。在国外，医院水源性感染已成为医院感染方面较为独立的研究领域。国内相关研究还处于起步阶段。本文从医院水源性感染相关概念、预防控制措施、医院水源性感染研究中存在的问题及我国现状展望对医院水源性感染进行介绍和评论。 【关键词】 　医院感染；水源性感染；预防控制 基金项目：卫生公益性行业科研专项“临床多重耐药菌医院感染防控研究及应用”(No.201002021)胡必杰；中华医院感染控制研究基金“多重耐药鲍曼不动杆菌生物膜对环境消毒剂的抗性研究及影响因素分析”(No.ZYGY011)周昭彦 Prevention and control of health-care associated waterborne infections in health care facilities ZHOU Zhao-yan, GAO Xiao-dong, HU Bi-jie* * Hospital Infection Control Unit, Zhongshan Hospital of Fudan University, Shanghai 200032, China. Corresponding author: HU Bi-jie, Email: hubijie@ Abstract Water has been recognized as the most important and controllable, yet the most overlooked, source of health-care associated infections (HAIs). Many research estimated that 25% HAIs has been connected with waterborne pathogens，while 14%-50% patients colonized/infected with Pseudomonas aeruginosa present the same clone with the isolates from tap water. Health-care associated waterborne infection has become an independent research field in oversea. However, it is at the stage of beginning in China. We will introduce and review it in four sections: related conception, prevention and control, the problem in front of us, and China’s current situation of Healthcare associated waterborne infection. 【Key words】 associated infection；Waterborne infection；Prevention and control This work was supported by Special Fund for Health-scientific Research in the Public Interest: Research application for the prevention control of nosocomial infections coursed by multi-drug resistant bacteria (No. 201002021) Hu Bijie; Research Fund for Chinese hospital infecton control: Efficacy of environmental disinfectants on multi-resistant Acinetobacter baumannii isolates in biofilm conditions (No.ZYGY011) Zhou Zhaoyan 尽管采取手卫生、接触隔离、合理使用抗生素等感染控制措施，医院感染仍时有发生，原因在于某些感染源和感染控制环节被忽视。水广泛用于医疗和病人护理，但水易滋生病原体，在自来水管道、医疗设备的水管道、甚至生活用具如淋浴喷头中形成难以清除的生物膜，对住院病人构成潜在感染威