硫酸镁在重症胰腺炎中应用对腹腔压力及hsCRP水平影响.docVIP

硫酸镁在重症胰腺炎中应用对腹腔压力及hsCRP水平影响 　　[摘要] 目的：观察硫酸镁在重症胰腺炎中应用对腹腔压力及hs-CRP水平的影响。方法：将66例诊断明确的SAP患者进行随机配对后分为硫酸镁治疗组和对照组。同时记录首次排便时间，并动态测定并记录血淀粉酶、hs-CRP值、腹腔压力水平。结果：硫酸镁治疗组平均排便时间早，所有患者在排便后血淀粉酶、hs-CRP值、腹腔压力降低明显，硫酸镁治疗组血淀粉酶、hs-CRP值、腹腔压力值较对照组明显降低，差异均有统计学意义（P<0.05）；并发症发生率以及中转开腹率、死亡率明显减少。结论：硫酸镁在重症胰腺炎的应用可以有效降低腹腔压力、减轻炎症应急反应，应该早期应用，可有效降低并发症的发生率。 　　[关键词] 硫酸镁 重症胰腺炎 hs-CRP 腹腔压力 　　[中图分类号] R657.51[文献标识码]Ａ [文章编号]1673-7210（2011）02（b）-030-03 　　The effect of magnesium sulphate used in severe acute pancreatitis on the the level of abdominal cavity pressure and hs-CRP 　　LIU Yongfan, ZENG Jian'geng, LIU Suhua, ZOU Meifeng, LIU Zhengfan 　　(Department of General Surgery, the Central People's Hospital of Ji'an City, Ji'an 343000, China) 　　[Abstract] Objective: To observe the effect of magnesium sulphate used in severe acute pancreatitis on the the level of abdominal cavity pressure and hs-CRP. Methods: 66 cases of SAP patients (diagnosis explicit) were divided into the magnesium sulfate treatment group and the control group. Simultaneously recorded for the first time of the bowel movement time, the dynamic determination, the blood amylase, the hs-CRP value and the abdominal cavity stress level. Results: Magnesium sulfate treatment group average bowel movement time was early, all patients after the bowel movement the blood amylase, the hs-CRP value, abdominal cavity pressure drop were obvious, the magnesium sulfate treatment group blood amylase, the hs-CRP value, the abdominal cavity pressure value, compared with the control group to reduce obviously, the difference had the significance (P<0.05). The incidence of the complication and the tranferred abdominal operation rate, the mortality significantly decreased. Conclusion: The magnesium sulfate can effectively reduce the abdominal cavity pressure and reduce the inflammation emergency reaction effectively when magnesium sulfate used in SAP; magnesium sulfate may be used early, it can reduce the complication effectively. 　　[Key words] Magnesium sulp