骨髓形态学结合外周血片检查对全血细胞减少性疾病诊断意义.docVIP

骨髓形态学结合外周血片检查对全血细胞减少性疾病诊断意义 　　[摘要]目的 探?骨髓形态学结合外周血片检查对全血涂细胞减少性疾病的诊断意义。方法 选取2010年1月～2017年6月我院收治的135例血细胞减少性疾病患者，根据血细胞减少类型分为A组（n=60，非全血细胞减少）和B组（n=75，全血细胞减少）。两组患者均进行外周血常规检查和骨髓形态学检查，统计两组患者的血小板（PLT）值、红细胞（RBC）值、白细胞（WBC）值、血红蛋白（Hb）值、平均血红蛋白浓度（MCHC）值、红细胞参数[红细胞平均体积（MCV）、红细胞平均血红蛋白量（MCH）]、血涂片检测结果，分析骨髓形态学结合外周血片检查在全细胞减少性疾病中的诊断价值。结果 A组患者的PLT值、RBC值、WBC值、Hb水平，均高于B组（P0.05）。结论 将骨髓形态学结合外周血片检查用于全血细胞减少性疾病效果理想，能提高临床诊断确诊率，值得推广应用。 　　[关键词]骨髓形态学；外周血片检查；全血细胞减少性疾病；诊断意义 　　[中图分类号] R551 [文献标识码] A [文章编号] 1674-4721（2017）12（b）-0156-04 　　[Abstract]Objective To investigate the significance of bone marrow morphology combined with peripheral blood smear examination in the diagnosis of pancytopenia.Methods A total of 135 patients with hematopoietic diseases who were admitted to our hospital from January 2010 to June 2017 were selected.According to the type of hemocytopenia，the patients were divided into group A （n=60，non-pancytopenia） and group B （n=75，pancytopenia）.Two groups of patients were all given routine examination of peripheral blood and bone marrow morphological examination.The levels of platelet（PLT），erythrocyte （RBC），leukocyte （WBC），hemoglobin （Hb），average hemoglobin concentration（MCHC），erythrocyte parametersaverage volume of red blood cells（MCV），and blood smear test results were statistically collected in both groups，and the diagnostic value of bone marrow morphology combined with peripheral blood smear examination in pancytopenia was analyzed.Results The levels of PLT，RBC，WBC cell and Hb in group A were all higher than those in group B （P0.05）.Conclusion Bone marrow morphology combined with peripheral blood smear examination used for pancytopenia has an ideal effect，which can improve the clinical diagnosis rate and is worthy to be popularized and applied. 　　[Key words]Bone marrow morphology；Peripheral blood smear examination；Pancytopenia；Diagnostic value 　　根据病理生理将全血细胞减少性疾病分为：①骨髓生成障碍；②外周血消耗过多[1]。全血细胞减少性疾病的病因复杂且病种较多，从总体上来看能分为造血系统疾病和非造血系统疾病[2-3]。常规实验室检查很难确定全血细胞减少性疾病患者的具体病因，临床医师除了询问病史外，还需对全