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非ST段抬高心肌梗死治疗-从临床实践到指南教学教案.ppt
案例-2 问题(3)抗栓治疗-抗血小板药物 阿司匹林? 剂量? 如不耐受? GPIIb/IIIa? 0.15 0.10 0.05 0.0 10 0 40 100 200 300 400 Cumulative hazard rates 31% RRR p=0.002 n=2658 Days of follow-up a b Placebo? Clopidogrel? The CURE Investigators. Lancet August 2001 a = median time from randomization to PCI (10 days) b = 30 days after median time of PCI ?up to 12 months ?In addition to standard therapy including ASA 12.6% 8.8% Composite of CV-death or MI from randomization to end of follow-up? PCI-CURE –Long-term Efficacy of Clopidogrel CREDO-Long-term Benefits of Clopidogrel in PCI Patients 27% RRR p = 0.02 Clopidogrel* Place
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