维持性血液透析过程中患者血压变异性及的影响因素的研究.docVIP

维持性血液透析过程中患者血压变异性及的影响因素的研究 　　[基金项目] 国家自然科学基金 　　 　　[摘要] 目的 研究维持性血液透析过程中患者血压变异性（BPV）及影响BPV增加的因素。方法 选择126例维持性血液透析患者，分别为低收缩压变异性组（LS-BPV组）63例和高收缩压变异性组（HS-BPV组）63例，低舒张压变异性组（LD-BPV组）63例和高舒张压变异性组（HD-BPV组）63例。结果 HS-BPV组和LS-BPV组年龄、透析龄、干体重、体质量指数、透析期间体重增长率、透析前SBP、白蛋白、血红蛋白、总胆固醇、钙磷乘积有显著差异（P＜0.05）。HD-BPV组和LD-BPV组年龄、干体重、体质量指数、透析间期体重增率、透析前SBP、透析前DBP、血红蛋白、钙磷乘积有显著差异（P＜0.05）。年龄、透析期间体重增长率、透析前SBP是收缩压BPV独立影响因素并呈正相关（P＜0.05），血红蛋白是收缩压BPV独立影响因素并呈负相关性（P＜0.05）。透析间期体重增率、透析前DBP是舒张压BPV独立影响因素并呈正相关性（P＜0.05）。结论 高龄、透析期间体重增长率增加、透析前高SBP、血红蛋白降低是维持性血液透析过程中患者收缩压BPV增加的独立危险因素；透析期间体重增长率增加、透析前高DBP是维持性血液透析过程中舒张压BPV增加的独立危险因素。 　　[关键词] 维持性血液透析；血压变异性；透析中血压；危险因素 　　[中图分类号] R459.5[文献标识码] A[文章编号] 1673-9701（2014）19-0015-04 　　 　　Risk factors of blood pressure variability in the process of maintenance hemodialysis 　　GAO Yan1 HUANG Kai2 　　1.NO.2 East Department of Nephrology，the First Peoples Hospital of Hangzhou City，Hangzhou 310006，China；2.Department of Cardiology, the Union Hospital, Tongji Medical College, Huazhong University of Science and Technology，Wuhan 430022，China 　　[Abstract] Objective To study blood pressure variability （BPV） and risk factors of BPV increasing for patients in the process of maintenance hemodialysis. Methods A total of 126 cases of hemodialysis patients, were divided LS-BPV group of 63 cases, and HS-BPV group of 63 cases, LD-BPV group of 63 cases, and HD-BPV group of 63 cases. Results HS-BPV group and the LS-BPV group age, duration of dialysis, dry weight , body mass index, weight increased during dialysis, pre-dialysis SBP, albumin , hemoglobin , total cholesterol, calcium-phosphorus product were statistically significance difference（P0.05）. HD-BPV group and LD-BPV group age, dry weight , body mass index , dialysis room rate of weight gain, pre-dialysis SBP, pre-dialysis DBP, hemoglobin, calcium-phosphorus product were statistically significance differences（P0.05）. Weight increased age, during dialysis, pre-dialysis systolic BPV SBP were independent factors and a posi tive