心房颤卒中预防指南解读.pptVIP

The prevalence of AF in the adult population doubles with each advancing decade of age from 0.5% at age 50-59 years to 9% at age 80-89 years (Fig. l). As aging proceeds there is gradual loss of nodal fibers and increase of fibrous and adipose tissue in the s韓o-atrial node (2). Decreased ventricular compliance occurs due to myocardial fibrosis resulting in atrial dilatation that has been shown to predispose to AF (3). Extensive senile amyloid infiltration of the sinoatrial node may occur (4). However, aging also 韓volves longer exposure to predisposing conditions, and even in advanced age some a