人类疱疹病毒()精美生物医学.pptVIP

Human herpes viruses 人 类 疱 疹 病 毒 Contains several of the most important human pathogens A spectrum of diseases Life long persistent infection Periodic reactivation Main properties Virion: spherical, 150-200nm core + capsid + envelope dsDNA, encodes at least 100 proteins 35 proteins structure of virus Replication: In the nucleus Bud from nuclear membrane Early replication and late replication CPE: apart from EBV, others can cause CPE in cell culture Form of infection Replication infection : primary, reactivated Latent infection Congenital infection (先天性感染) Cell transformation