低剂量复合螺旋藻多糖抗衰老作用研究.PDFVIP

, Jou n al of Anhu iAg .i Sci. 2010, 38( 20) : 11036- 11038 常俊香 卢瑶 1 2 2 2 2* 唐纯青 , 于蕾妍 , 张 丽 , 高玲 , 王清吉 ( 1. , 250022; 2. , 266109) 每天给小鼠灌服 50 mg /kg复合药物, 同时每天给其颈背皮下 射D半乳糖 125 mg /kg, 连续造模 42 d后观察低剂量复合螺旋藻 多糖银杏叶提取物对D半乳糖致衰老小鼠的作用, 测定免疫器官的重量血清 SOD 活性及心肌脑丙二醛(MDA )含量等相关衰老指 标结果表明, 低剂量复合螺旋藻多糖可显著对抗连续 42 d给 D半乳糖 125 mg / ( kg. d)所致小鼠衰老 螺旋藻多糖; 银杏叶提取物; D半乳糖;衰老 R 965 A 0517 - 6611( 2010) 20- 11036- 03 Study on Antiaging Function ofLow- dosage Compound Spirulina Polysaccharides th TANG Chunqing et al ( The Thi d M edical D epa tm en,t T he 5 P eople s H ospital o f Jinan C ity in Shandong P ovince, J inan, Shandong 250022) Abstract The m ice w e e d enched w ith 50 mg /kg compoundm edicine and smi ultaneously injectedw ith 125 mg /kg Dga lactose by hypode m ic injection in nape eve yday. A fte continuously modeling fo 42 d, the effects o f low dosage compound sp iulina po lysaccha ides and g ingko leaf ex t acts on Dgalactosecaused agedm ice w e e obse ved and the ag inge lated indexes ofw eight of mi mune o gan, SOD activ ity in se um, MDA con tents in ca diac muscle and b ain w e e dete m ined. The esults indicated that low dosage compound spi ulina polysaccha ides had sign ificant anti ag ing effect on aged m ice, w hich w e e modeled by continuously giving 125mg / ( kg. d) Dgalactose fo 42 d. Key words Spiu lina polysaccha ides; G ingko leaf ext acts; DGalactose; A ging ), , , , . 2. 2 7 d, 21, , 9VE , 100 50 mg /( kg! d); , , . 2. 3 [ 2]D, , , , 0. 5% , D 125 m g/ ( kg! d) , 42 d . . 3 . . . 3. , , , [ 1], ( PSP), 93%