乳腺良恶性病变及正常女性乳腺密度类型分析-海南医学.PDF

Hainan Med J, Aug. 2015, Vol. 26, No. 15 海南医学2015年8月第26卷第15期 doi:10.3969/j.issn.1003-6350.2015.15.0811 ·论 著· 乳腺良恶性病变及正常女性乳腺密度类型分析 吴志娟，黄建康，朱玉春 ( 昆山市第一人民医院放射科，江苏 昆山 215300) 【摘要】 目的 比较乳腺恶性、良性病变及正常女性的乳腺密度类型，分析各年龄阶段不同类型乳腺密度 的恶性和良性病变检出率。方法 收集首次接受全数字化乳腺摄影检查的4 241 例女性患者的临床资料。根据 乳腺腺体成分所占百分比将乳腺密度分为4 型，即75% 、51%~75%、25%~50%和25% 。乳腺影像存在异常时进 一步行病理学检测以确定病变性质。结果 乳腺密度随年龄的增加逐渐下降；乳腺恶性病变、良性病变及正常 女性之间的乳腺密度类型构成比差异有统计学意义(P0.05) ；年龄≥40 岁恶性病变检出率随乳腺密度减低逐渐 升高(P0.01) ，年龄40~60 岁良性病变检出率随乳腺密度减低逐渐降低(P=0.037) 。结论 乳腺密度作为一项影 像检查指标评估乳腺病变风险具有重要价值，不同年龄女性人群中乳腺密度对乳腺良性和恶性病变的风险尺度 和效应不一致。 【关键词】 乳腺密度；乳腺；良性；恶性 【中图分类号】R737.9 【文献标识码】A 【文章编号】 1003—6350（2015 ）15—2249—05 Analysisontypeofmammographicdensityamongwomenwithmalignant,benignbreastlesionsandnormal breasts. WUZhi-juan,HUANGJian-kang,ZHUYu-chun.DepartmentofRadiology,theFirstPeoplesHospitalof Kunshan,Kunshan215300,Jiangsu,CHINA 【Abstract】 Objective To compare the types of mammographic density among women with malignant, be- nign breast lesions and normal breasts, and to analyze the detection rate of women with malignant and benign breast lesions by age and type of mammographic density. Methods The clinical data of 4 241 women that accepted digitized film images with computerized techniques examination for the first time were collected. Four types of mammographic density were determined according to percentage of fibroglandular tissue, 75%, 51%~75%, 25%~50% and 25%. A fur- ther pathological detection was performed to determine the lesions type when there was abnormal breast imaging. Results The descending of mammographic density was associated with age, and statistically differences