2018ILTS建议_非酒精性脂肪性肝炎的管理和治疗.pdf

Recommendations for management and treatment of nonalcoholic steatohepatitis 1 2 3 Vlad Ratziu , Marwan Ghabril , Manuel Romero-Gomez , Gianluca Svegliati- Baroni4,5 1 Sorbonne Université, Institute for Cardiometabolism and Nutrition, Hospital Pitié Salpêtrière, INSERM UMRS 1138, Paris France; 2 Division of Gastroenterology and Hepatology, Indiana University School of Medicine, Indianapolis, Indiana, USA; 3 University Hospital, Virgen del Rocio, Institute of Biomedicine of Seville, University of Seville, Sevilla, Spain; 4,5 Department of Gastroenterology and Obesity Center, Polytechnic University for Marche, Ancona, Italy. Corresponding author: Prof V Ratziu, vlad.ratziu@inserm.fr Conflicts of Interest: Vlad Ratziu: consultancy or advisory board meetings for Allergan, Boehringer, Galmed, Genfit, Intercept, Novartis, Novo-Nordisk. Marwan Ghabril: Research support Salix Pharmaceutical. Manuel Romero-Gomez: consultancy or advisory board meetings for Allergan, Intercept, Medimmune, Gilead, Novo-Nordisk. Gianluca Svegliati-Baroni: Advisory board meetings for Gilead 1 Authorship contributions: All authors took part in the meeting, the discussions and provided input on the grading of recommendations. Specific contributions include: Marwan Ghabril, text on physical exercise, Manuel Romero-Gomez, text on dietary interventions, Gianluca Svegliati-Baroni, text on alcohol consumption, Vlad Ratziu, text on pharmacological therapy. Vlad Ratziu was responsible for editing of the whole document and all authors approved the final version.