scin促进胃癌细胞侵袭机制及胃肠道间质瘤细胞系的建立外科学普外专业论文.docxVIP

第三军医大学硕士学位论文缩略语表 第三军医大学硕士学位论文 缩略语表 英文缩写 英文全称 中英对照 SCIN scinderin 肌切蛋白 GIST gastrointestinal stromal tumor 胃肠道间质瘤 Cm centimeter 厘米 FBS fetal bovine serum 胎牛血清 DEPC diethy pyrocarbonate 焦碳酸二乙酯 IⅢA ribonucleic acid 核糖核酸 CCK．8 cell counting kit-8 细胞计数试剂盒8 EDTA ethylene diamine tetraacetic acid 乙二胺四乙酸 FITC fluorescein isothiocyanate 异硫氰酸荧光素 g gram 克 DNA deoxyribonucleic acid 脱氧核糖核酸 HRP horseradish peroxidase 辣根过氧化物酶 h hour 小时 PVDF polyvinylidene fluoride 聚偏二氟乙烯 HE hematoxylin-eosin 苏木精伊红 DMS0 dimethyl sulphoxide 二甲基亚砜 ECL electrochemiluminescence 电化学发光 d day 天 Cdc42 cell division cycle 42 细胞分裂周期蛋白 42 ml milliliter 毫升 OD optical density 光密度 PCR polymerase chain reaction 聚合酶链式反应 min minute 分钟 PBS phosphate buffer solution 磷酸盐缓冲液 PAGE polyacrylamide gel electrophoresis 聚丙烯酰胺凝胶电 泳 ng nanogram 纳克 Tris Tris(hydroxymethyl)aminomethane 三羟甲基氨基甲烷 d day 天 IC50 half maximal inhibitory concentration 半抑制浓度 万方数据 第三军医大学硕士学位论文Mechanism 第三军医大学硕士学位论文 Mechanism of SCIN·-promoting invasion in gastric cancer cells and establishment and characterization of a new gastric GIST cell line Abstract Part I Study on the mechanism of SCIN-promoting invasion in gastric cancer cells Background and objective： Gastric cancer(GC)is the fourth-most prevalent cancer worldwide and the second-most common cause of cancer-related death．Although the mortality rate has been decreasing over recent years due to significant improvements in early diagnosis，surgical techniques and chemotherapy，the long—term survival rate for patients with advanced-stage GC still remains low．Many GC patients suffer from recurrence or metastasis after radical operation and chemotherapy，leading to a more complicated situation for further treatment and reoperation．Invasion and metastasis are important properties of GC that contribute to poor prognosis of patients and the underlying mechanisms still remain unclear．Therefore，better understanding of the molecular mechanisms underlying invasion and metastasis of GC is crucial for the effec