支气管内超声两种回声特征在判断肺部周围型病灶良恶性中.PDF

·1016 · 南方医科大学学报（J South Med Univ ） 2012;32(7) 临床研究 临床研究 支气管内超声两种回声特征在判断肺部周围型病灶良恶性中的 应用 黄 禹，陈正贤，任红岩，何碧芳，黎秀玉 广东省人民医院呼吸内科，广东 广州 510080 摘要：目的评估将支气管内超声（EBUS）两种简易的回声特征应用于判断肺周围型病灶良恶性的可行性。方法 分析102名接 受EBUS 检查的肺周围型病变患者的EBUS 图像，了解这两种回声特征对周围型肺癌诊断的敏感性和特异性。结果 晕环征，实 性低回声是提示周围型病灶为恶性的两种回声特征。实性低回声在诊断恶性病变时敏感性较高（89.46% ），特异性也较高 （83%），晕环征的敏感性为69.51% ，特异性为65%。只要存在任何一种回声特征，诊断恶性的敏感性可达94.6% ；两种回声特征 同时存在时，诊断恶性的特异性可达93%。结论 对于常规支气管镜检查未能显示的周围型病灶，我们通过EBUS 的这两种回 声特征可较为快速、准确的诊断周围型肺癌。 关键词：支气管内超声；回声特征；周围型肺癌 中图分类号：R562.2 文献标志码：A 文章编号：1673-4254（2012）07-1016-04 doi: 10.3969/j.issn. 1673-4254.2012.07.025 /kcms/detail/44.1627.R1136.008.html Differential diagnosis of malignant and benign peripheral pulmonary lesions based on two characteristic echo features of endobronchial ultrasonography HUANG Yu, CHEN Zhengxian, REN Hongyan, HE Bifang, LI Xiuyu Department of Respiratory Diseases, Guangdong General Hospital, Guangzhou 510080, China Abstract: Objective To assess the feasibility of endobronchial ultrasonography (EBUS) in the differential diagnosis of malignant and benign lesions based on the two characteristic echo features of malignancy. Methods EBUS images from 102 patients undergoing bronchoscopy for peripheral lung lesions were analyzed. The sensitivity and specificity were determined for each echo feature, namely the halo sign and low-level echoes that indicated malignancy, or their combination in diagnosing malignant and benign lesions. Results Low-level echoes showed a sensitivity of 89.46% and a specificity of 83% in the diagnosis of malignancy, both higher than those of the halo sign (69.51% and 65%, respectively). The presence of either of the two echo features had a diagnostic sensitivity of 94.6% for malignant lesions, and the coexistence of the two features had a spe