汕头大学医学院药理学皮肤病与性病学课件 药疹.pptVIP

* * Drug eruption (Dermatitis medicamentosa) 一.Definition 二.Etiologic Factors (Etiology) （一）The individual factors （二）Drugs （二）Drugs Antibiotics 2. Antipyretic-analgesic drugs 3. Sedative-hypnotic drugs and Antiepileptic drugs 4 .Antigout (allopurinol) 5.Heterologous(Foreign) serum and Vaccine etc. 6. Traditional chinese medicine 三.Pathogenesis: （一） Allergic （二） Nonallergic 四.Clinical Findings: （一）Fixed drug eruption： Antipyretic-analgesic drugs Sulfonamides Barbiturates （二）Urticarial drug eruption： Heterologous(Foreign) serum、 Furazolidone、Penicillin （三）Morbilliform drug eruption and Scarlatiniform drug eruption： Penicillin Sulfonamides Antipyretic-analgesic drugs Barbiturates （四）Eczematous drug eruption： Penicillin Streptomycin Sulfonamides Quinine （五）Purpuric drug eruption： Antibiotics Barbiturates Diuretics （六）Erythema multiforme drug eruption： Sulfonamides Antipyretic-analgesic drugs Barbiturates （七）Drug-induced bullosa epidermolysis： Sulfonamides Antipyretic-analgesic drugs Antibiotics Barbiturates （八）Drug-induced exfoliative dermatitis： Sulfonamides Barbiturates Antiepileptic drugs Antipyretic-analgesic drugs Antibiotics （九）Acneiform drug eruption： Glucocorticoid *