血浆置换和血浆灌流联合治疗肝衰竭患者不良反应观察.PDFVIP

年 月第 卷第 期 ·临床研究 · 2012 9 19 26 血浆置换与血浆灌流联合治疗肝衰竭患者的 不良反应观察 蒋玉凤 倪 艳 王 英 泸州医学院附属医院感染病科，四川泸州 646000 摘要 目的观察血浆置换联合血浆灌流治疗肝衰竭患者不良反应的发生。 方法 序贯应用血浆置换联合血浆灌流 [ ] 治疗 例慢加急性肝衰竭患者共 例次，观察并总结治疗中及治疗后 内不良反应发生情况。 结果 治疗过 68 146 24 h 程中与治疗后24 h 内总体不良反应发生率低（21.2% ），以低钙致口唇麻木最常见，无严重不良反应发生，所有不良 反应经对症治疗均缓解， 无一例患者因不良反应导致死亡。 结论 血浆置换联合血浆灌流治疗肝衰竭不良反应发 生少，是治疗肝衰竭安全有效的方法。 关键词 血浆置换；血浆灌流；肝衰竭；不良反应 [ ] 中图分类号 文献标识码 文章编号 （ ） （ ） [ ] R575.3 [ ] A [ ] 1674-4721 2012 09 b -0064-02 Observation of adverse reactions in combination therapy of plasma exchange and plasma perfusion in patients with liver failure JIANG Yufeng NI Yan WANG Ying Department of Infectious Diseases, the Affiliated Hospital of Luzhou Medical College in Sichuan Province, Luzhou 646000, China [Abstract] Objective To observe the adverse reactions of combination therapy of plasma exchange (PE) and plasma perfu - sion (PP) in patients with liver failure. Methods There were totally 146 person-times including 64 patients who received a combination therapy of PE and PP, and patients with acute liver failure. The occurrence condition of adverse reactions dur - ing treatment and in 24 hours after treatment were closely observed and summarized. Results The total adverse reaction rate during treatment and in 24 hours after treatment