宫颈锥切术对生育能力及妊娠结局的影响-肿瘤药学.PDFVIP

- 198 - 肿瘤药学 2019 年 4 月第 9 卷第 2 期　Anti-tumor Pharmacy, April 2019, Vol. 9, No. 2 ●综　　述● 宫颈锥切术对生育能力及妊娠结局的影响 * 袁　礼 ，许向宁，黄巧丽，陈亦乐 （湖南省肿瘤 医院/ 中南大学湘雅 医学院附属肿瘤 医院，湖南 长沙，4 10000 ） 摘要：近年来，宫颈上皮内瘤样病变（CIN）Ⅲ行宫颈锥切术取代了传统的子宫切除术，减少了对孕龄妇女生殖系统的不 良影响。但因锥切术将部分宫颈组织进行切除，可能对患者术后生育能力及妊娠结局造成一定程度的影响。目前锥切术对 患者生育能力及妊娠结局的具体影响尚不明确。较多学者认为宫颈锥切术会增加不孕不育的风险及辅助生育的可能。但也 有不少临床研究认为宫颈锥切术不会影响患者的生育能力及妊娠结局。总之，宫颈锥切术对生育能力及妊娠结局的影响尚 无统一定论。本文就锥切术对生育能力及妊娠结局的影响的研究进展作一综述。 关键词：宫颈 CIN Ⅲ；锥切术后；生育能力；妊娠结局 中图分类号：R713.4　文献标识码 ：A　文章编号：2095-1264（2019）02-0198-06 doi：10.3969/j.issn.2095-1264.2019.02.05 Analysis on the Fertility and Pregnancy Outcome after Cervical Conization * YUAN Li, X U Xiangning, H UANG Qiaoli, CHEN Yile (Hunan Cancer Hosp ital / The Aff iliated Cancer Hosp ital of Xiangya School of Medicine, Central South University, Changsha, Hunan, 410013, China) Abstract: In recent years, CIN Ⅲ cervical conization has replaced traditional hysterectomy, reducing the adverse effects on the repro- ductive system of women of gestational age. However, due to the removal of part of the cervical tissue by conization, it may have a certain degree of influence on postoperative fertility and pregnancy outcomes. At present, the specific impact of cervical conization on fertility and pregnancy outcomes is still not clear. Some scholars believe that cervical conization will increase the risk of infertility and the possibility of assisted reproduction. However, there are also many clinical studies showed that cervical conization does not affect patients fertility and pregnancy outcomes. In short, there is no con