02－1型糖尿病病因学.pptVIP

* * * Slide II/3 Type 2 diabetes depends on a combination of low acute insulin response (secretion) and low glucose uptake (sensitivity). Six-year cumulative incidence has been shown to be much greater when both factors are present than when one factor or the other exists alone.57 胰岛素分泌与作用的关系 正常对照 运动员 肥胖非糖尿病患者 肥胖糖尿病患者 胰岛素分泌 胰岛素作用 胰岛素敏感性/分泌 与2型糖尿病的危险因素 Adapted from Lillioja S et al N Engl J Med 1993;329:1988-1992. 累及发病率 (%) 胰岛素分泌 低 低 高 高 胰岛素敏感性 40 30 20 10 0 40 30 20 10 0 * 9 9 9 * 9 9 9 * * * 9 9 9 * * * * * 9 9 9 * * * * * * * * * * * 2 2 * * * * Patientmaterialet bestod af 39 diabetes pati