皮质脊髓束与脑卒中患者运动功能预后的相关研究进展.PDF

中国康复理论与实践2018年11月第24卷第11期ChinJRehabilTheoryPract,Nov.,2018,Vol.24,No.11 - 1280 - DOI: 10.3969/j.issn. 1006-9771.2018.11.007 ·综述 · 皮质脊髓束与脑卒中患者运动功能预后的相关研究进展① 王瑜元，白玉龙 复旦大学附属华山医院北院康复医学科，上海市201907 通讯作者：白玉龙。E-mail: dr_baiyl@ 基金项目：1. 国家自然科学基金项目(No. ；2. 上海市卫计委青年科研项目(No. 20154Y0047; No. 20164Y0235) 摘要 皮质脊髓束(CST)是重要的随意运动传导通路。CST 损伤影响脑卒中患者运动功能，尤其是上肢运动功能恢 复，并与患者长期运动功能预后相关。CST 在脑卒中后可发生皮质水平和皮质下重塑，从而促进运动功能恢 复。CST 重塑机制复杂，需要进一步研究。 关键词 脑卒中；皮质脊髓束；轴索重塑；综述 Advance in Corticospinal Tract and Motor Recovery after Stroke (review) WANG Yu-yuan, BAI Yu-long Department of Rehabilitation Medicine, Huashan Hospital of North, Fudan University, Shanghai 201907, China Correspondence to BAI Yu-long. E-mail: dr_baiyl@ Supported by National Natural Science Foundation of China (No. and Shanghai Municipal Commission of Health and Family Planning Research Preject (Youth) (No. 20154Y0047; No. 20164Y0235) Abstract Corticospinal tract (CST) is the major neuronal pathway that mediates voluntary movements, and the severity of injury may influence the recovery of motor function, especially that of the upper limbs, and involve to the long-term outcome. Axonal remodeling may happen in the CST after stroke, at the levels of spine and brain, which promotes the recovery of motor function. The mechanism of remodeling is complicated, and need more researched. Key words: stroke; corticospinal tract; axonal remodeling; review [中图分类号] R743.3 [文献标识码] A [文章编号] 1006-9771(2018) 11-1280-04 [本文著录格式] 王瑜元，白玉龙. 皮质脊髓束与脑卒中患者运动功能预后的相关研究进展[J]. 中国康复理论与 实践, 2018, 24(11): 1280-1283. CITED AS: Wang YY, Bai YL. Advance in corticospinal tract and motor recovery after stroke (review) [J]. Chin J Reha- bil Theory Pract, 2018, 24(11): 1280-1283. 皮质脊髓束(cor