恶性潜能未定型子宫平滑肌肿瘤12例临床病理分析.pdfVIP

2007 11 23 11 　Journal of Practical Obstetrics and Gynecology 2007 Nov .Vol .23,No.11 ·677 · :1003-6946(2007)11-677-03 　 恶性潜能未定型子宫平滑肌肿瘤12 例临床病理 分析 1 1 1 2 3 1 冯　静,王建六,苗娅莉, 彭学玲,朱崇云,魏丽惠 (1., 100044;2., 256100;3., 276003) 【】　:探讨恶性潜能未定型子宫平滑肌 瘤的临床表现、组织病理学和影像学特征以及 治疗和预后。:选择因子宫平滑肌 瘤于我院行手术治疗,病理诊断为恶性潜能未定型子宫 平滑肌 瘤12 例进行回顾性分析,并对患者进行随访。:恶性潜能未定型子宫平滑肌 瘤 占子宫平滑肌 瘤的0.88%, 平均发病年龄为42.67 岁, 11 例患者未绝经, 结节直径平均8.41 cm,5 例结节内部血流阻力指数0.4,2 例患者血清CA125 水平高于正常。1例绝经前患者术后半 年盆腔复发, 1 例绝经患者术后3 年盆腔发生平滑肌肉瘤。:B 超及血清CA125 等检查可能难 以在术前诊断恶性潜能未定型子宫平滑肌 瘤,病理检查为确诊手段。该 瘤目前尚无统一的 临床治疗手段,应进行密切随访,预后较好。 【】　恶性潜能未定型子宫平滑肌 瘤;子宫平滑肌肉瘤;血流阻力指数 :R737.33 　　　　:A Clinico-pathological Analysis of Smooth Muscle Tumor with Uncertain Malignant Potential: 12 Cases Reports FENG Jing,WANG Jianliu, MIAO Yali, et al (Peking University Peoples Hospital, eijing 100044, China) Corresponding author:WANG Jianliu 【Abstract】　Objective:To investigatethe clinical, histopathological, radiological features of smooth muscle tumorwith uncertain malig- nant potential and the appropriatetreatments.Methods:12 Cases diagnosed as smooth muscletumor with uncertain malignant potential from January, 2000 to December, 2005 were chosento be analyzed.Follow-upwasperformed.Results:Smooth muscletumorwith un- certain malignant potential accounted for 0.88%of all uterine smooth muscletumors.The meanage of onset was 42.67years with 11 premenopausal women.The mean size of thetumorwas 8.41cm, 5 patients with tumor resistance index less than0.4.2 patients got serum CA125 more than 35U/ml.1 premenopausal patient presented pelvic recurrence within 0.5 years after leiomyoma resection, and another 1patient got pelvic leiomyosarcoma 3 years after hysterectomy and bisalpingo-oopharectomy.Conclusions:Ultrasound scanand serumCA examination may not help to makethe diagnosis of smooth muscle tumor with uncertain malignant potential before oper