膳食纤维和体重控制.ppt

膳食纤维与体重控制 Dietary fiber and weight management 张爱珍 zhang aizhen 量A 折江火学城市学院医学与生命科学学院 膳食纤维与体重控制 Dietary fiber and weight management 膳食纤维摄入量与体重、体脂呈负相关 Most but not all observational studies showed an inverse sometimes dose-dependent relationship between DE consumption and body weight obesity is strong 水溶性膳食纤维和非水溶性膳食纤维 对体重 富含膳食纤维的天然食物和膳食纤维制剂 控制效 果类似 Generally, in human studies, no clear difference regarding weight gain has been shown between soluble and insoluble DF and fermentable and nonfermentable df or between foods naturally high in DF and fiber supplements 膳食纤维与体重控制 Dietary fiber and weight management 膳食纤维控制体重的可能机制 1含亲水基团,吸水膨胀性匚腹感 Intervention studie ary nber genera stake and, hence, 2粘性、吸附性 E缓饥饿感 Inducing greater satiation and satiety Decreasing absorption or 3在大肠内发酵代谢供能量较少 Altering secretion of gut hormones 4减少营养素吸收 Decreasing in energy intake and body 5改变肠道激泰分泌 mechanisms 国外的研究:膳食纤维与体重控制 Dietary fiber and weight management 能量摄入:减少10%(消瘦者:6%肥胖/超重者:18%) 体重:减轻19kg(消瘦者:0.8kg肥胖/超重者:24kg) Howarth et al: mean values for published studies indicate that EpIdemiologic suppor: umption of an additional l- p/day liber for >2 day 出 DF InTake preven ociated with a Ioo decrease in energy intake and body weight ss of 1.9 kg over 3.8 mont mean energy intake in all studies was reduced to 82%e by higher fiber intake in overweightobese people versus 94%e in lean people: body weight loss was 2.4 kg versus 0.8 kg 「对超重/肥胖症患者减轻体重的效果优于健康体重者 obese individuals may exhibit a greater suppression of energy intake and body weight loss 我们的研究:McP对肥胖大鼠血脂及瘦素的调节 实验各组大鼠体重的变化情况(g,x土s) 组别 实验前体重 第2周 第6周 空白对照组 203.5±8.5 264.4±197 367.7±294 高脂模型组 202.2±94 281.2±16.8☆☆ 401.7士33.2☆☆ MCP低剂量组 204.5士78 287.3±13.1☆☆ 396.1±318☆☆ MCP中剂量组2036±73284.7±12.6☆☆ 398.3±215☆☆ MCP高剂量组202.5±84 276.8±125☆ 383.2±30.9 dy oF DF in rat