《妇产科学》课件：第22章第4节宫颈癌 双语.pptVIP

etiology Human PapillomaVirus (HPV) infection other risk factors RISK FACTORS Multiple sexual partners Early onset of sexual activity Low socioeconomic status Long-term oral contraceptive use High parity cigarette smoking HPV INFECTION HPVs are major etiologic factor in the development of CIN and cervical cancer about 100% cervical cancer and 80% CIN are HPV positive Low-risk HPV: 6, 11, 42, 43, 44 and so on are associated to CINⅠand condyloma (genital warts) High risk HPV: 14 types including HPV16, 18, 31, 33,35, 56, 58...CINⅡ/Ⅲ and cervical cancer HPV16/18 accounts for 70% cases of cervical