神经精神药理英文课件：ANTIDEPRESSANTS.pptVIP

Anti-Manic Drugs or Mood Disorder Lithium (Li+) remains the drug of choice for the treatment and prophylaxis of mania. Acute manic episodes are managed with lithium salts (carbonate or citrate) alone, or in combination with: 1) Antipsychotics 2) anticonvulsive,e.g. Valproic acid, carbamazepine(similar in structure to TCAs but not effective in depression). 3) Calcium-channel blockers (nifendipine硝苯吡啶 , diltiazem地尔硫卓 , verapamil异搏定 ). Lithium (Li+) A number of salts of lithium are used as mood-stabilizing drugs, primarily in the treatment of bipolar disorder, where they have a role in the treat