12、国外大学研究所收集sanger研究所chapter5.pdfVIP

Identification and Characterization of Regulatory Elements on Human Chromosome 20q12-13.2 5 ANALYSIS OF 3.5 MB REGION ON 20q12-13.2 USING ChIP- CHIP Gene regulation is a complex process, requiring a large number of proteins acting cooperatively on specific DNA sequences, which are wrapped with histone proteins. Although instructions for the recruitment of the correct factors onto transcription initiation sites are stored in the DNA sequence, it should be decorated with the correct epigenetic markers to permit functional interac