国产与进口硝苯地平控释片治疗高血压病比较.docVIP

国产与进口硝苯地平控释片治疗高血压病比较 目录 TOC \o 1-9 \h \z \u 目录 1 正文 1 文1：国产与进口硝苯地平控释片治疗高血压病比较 1 1 临床资料 3 2 研究方法 4 3 结果 6 4 讨论 8 文2：国产与进口硝苯地平控释片治疗高血压病比较 9 参考文摘引言： 14 原创性声明（模板） 16 文章致谢（模板） 16 正文 国产与进口硝苯地平控释片治疗高血压病比较 文1：国产与进口硝苯地平控释片治疗高血压病比较 Domestic vs imported nifedipine controlled release tablets in treatment of essential hypertention 【Abstract】 Objective To evaluate the clinical efficacy and advee reactio of domestic nifedipine controlled release tablets in the treatment of essential hypertent5HZ〗 Methods One hundred and twety patients with EH were included. A study randomized was conducted. Sixty patients were treated with domestic nifedipine controlled release tablets(Test group)， 30～60mg/d and another sixty patients were treated with imported nifedipine controlled release tablets(Control group) 30～60mg／d for 8wk. Blood pressure were taken before and after domestic vs imported nifedipine controlled release tablets treatment. 24 hour ambulance blood pressure， blood and urine routine， blood biochemics， ECG were examined before and after treatment. Results The total effective rate of domestic nifedipine controlled release tablets was 95%，remarkable effective rate of domestic nifedipine controlled release tablets was 78%； while those of imported nifedipine controlled relesse tablets were 97% and 82%， there was no significant difference( P ＞). Blood and urine routine， blood biochemics were unchanged before and after treatment ； the advee reactio were mild. At the end of the 8th week， the two group the mean SBP/DBP of 24h， day-time and night-time were obviously decreased and had significant difference before and after taken( P ). SBP and DBP were decreased and had significant difference at every time point of 24h-ABPM in treatment( P ). The advee reaction rates in test and control groups were % and % ， respectively， and the withdrawal rates were % and % ， respectively. No statistical significant difference ( P ) between the patients in test and contro