预防手术部位感染基础措施.pptVIP

中南大学湘雅医院吴安华 * 抗菌药物给药时间对手术部位感染率地影响 2847 patients undergoing elective clean or clean-contaminated surgical procedures. Patients divided into 4 categories based upon timing of administration of antibiotic Early 2-24 hours before surgery Pre-operatively 0-2 hours before surgery Perioperative 0-3 hours after surgery Post-operative 3-24 hours after surgery 感染率 使用时间 3.8% 早期 0.6% 术前 1.4% 术后早 3.3% 术后晚 Classen DC, et al:N Engl J Med 1992 中南大学湘雅医院吴安华 * 围手术期用药 对抗菌药物要求 1,抗菌谱广