假性垂体瘤英文及病例.pptxVIP

假性垂体瘤英文及病例第1页/共19页 English Case reportDiagnosis and Therapy of Pituitary pseudotumor (pituitary thyrotroph hyperplasia) Neurosurgery Department 第2页/共19页 English Case reportNowadays more and more lesions in saddle area are found by CT and MRI especially pituitary adenoma.Do you think all lesions in saddle area can be diagnosised pituitary adenoma?第3页/共19页 English Case reportMany patients diagnosised pituitary adenoma preoperation was demonstrated to be hyperplasia or Pituitary pseudotumor ,but not tumor.So, what led us to the misdiagnosis? 第4页/共19页 English Case reportWhat is so-called “Pituitary pseudotumor” or “ pituitary hyperplasia”?第5页/共19页 English Case reportThyriod gland, suprarenal gland, ovarianhypothalamusThe axis of hormone control in our bodyControl functionReverse feedback第6页/共19页 English Case reportThat is to say “the shape and function of pituitary is controlled by hypothalamus and feedback-affected by target organs such as Thyriod gland suprarenal gland ovarian第7页/共19页 English Case reportThe way that made these control goes is based on the hormone, such as TSH, ACTH, PRL, FSH, LH, GH T3T4, virosterone, cortisol, E2第8页/共19页 English Case reportCase 1 famale, 15years, complained “delayed growth ,acratia and a blur eyesight for 5 months”. Hormone tests showed decreased T3T4 level mardkedly high TSH level(75mIU/L)第9页/共19页 English Case reportABCDpicture A-C demonstrate a larger pitutary gland,which grow upward like a ball with a clear boundary. The optic nerve and chiasm were raised.There’s no difference between lesion and posthypophysis. Picture D shows a delayed growth of the bone in wrist(about 5-6years compared to normal children).第10页/共19页 English Case reportNow, do you still keep the diagnosis of pitutary adenoma in your mind