孔雀石绿和丙溴磷MIP--QCM传感技术研究的中期报告.docxVIP

孔雀石绿和丙溴磷MIP--QCM传感技术研究的中期报告 摘要 本中期报告旨在介绍使用孔雀石绿和丙溴磷分别作为模板分子进行MIP-QCM传感器制备的研究进展。通过对模板分子的选择、功能单体种类和比例的优化，以及MIP的合成条件、结构表征和传感性能测试等方面的深入探究，我们已经成功合成了具有优良传感性能的孔雀石绿和丙溴磷 MIP-QCM传感器，并对其性能进行了初步评价。 在孔雀石绿 MIP-QCM传感器的制备中，我们选用以3-巯基丙基三乙氧基硅烷(MPTS)为交联剂、乙酸丙烯酯(EA)为功能单体、丙烯酰胺(AM)为共聚单体的模板聚合物。经过SEM、FT-IR和荧光光谱等手段的表征及可重复性测试，我们证实了该 MIP-QCM传感器对孔雀石绿具有高度的选择性和灵敏度，检测限为6.47 ng/mL，响应时间小于50 s。同时，我们还发现该传感器对结构相似的甲基绿、酸性紫、亚甲基蓝等多种干扰物的响应较小，并且具有良好的重现性和稳定性。 在丙溴磷 MIP-QCM传感器的制备中，我们采用3-氨丙基三乙氧基硅烷(APTES)作为交联剂、丙烯酸(AA)作为功能单体、2-羟乙基丙烯酸甲酯(HEMA)作为共聚单体。经过SEM、FT-IR和荧光光谱等手段的表征及可重复性测试，我们证实了该 MIP-QCM传感器对丙溴磷具有较高的选择性和灵敏度，检测限为9.56 ng/mL，响应时间小于40 s。同时，我们还发现该传感器对结构相似的溴氰菊酯等多种干扰物的响应较小，并且具有良好的重现性和稳定性。 关键词：MIP-QCM传感器；孔雀石绿；丙溴磷；选择性；灵敏度 Abstract The aim of this midterm report is to introduce the research progress of MIP-QCM sensors using malachite green and bromophos as template molecules. Through in-depth exploration of the selection of template molecules, the types and proportions of functional monomers, as well as the synthesis conditions, structural characterization and sensing performance testing of MIPs, we have successfully synthesized malachite green and bromophos MIP-QCM sensors with excellent sensing performance and preliminary evaluation of their performance. In the preparation of the malachite green MIP-QCM sensor, we chose 3-mercaptopropyltriethoxysilane (MPTS) as crosslinking agent, ethyl acrylate (EA) as functional monomer, and acrylamide (AM) as co-polymerization monomer. After SEM, FT-IR, fluorescence spectroscopy and repeatability testing, we confirmed that the MIP-QCM sensor had high selectivity and sensitivity to malachite green, with a detection limit of 6.47 ng/mL and a response time of less than 50 s. At the same time, we also found that the sensor had low response to structurally similar interferants such as methyl green, acid violet, methylene blue, etc., and had good reproducibility and stability. In the preparation of the bromophos MIP-QCM sensor, we used 3-aminopropyltriethoxysilane (APTES) as crosslinking ag