MBD2蛋白在肿瘤CpG岛甲基化信号传递中的作用研究的中期报告.docxVIP

MBD2蛋白在肿瘤CpG岛甲基化信号传递中的作用研究的中期报告 Abstract: The methylation of CpG islands in tumor cells is an important epigenetic modification that can lead to tumor suppressor gene silencing, oncogene activation, and tumor progression. MBD2 protein is known to play a critical role in CpG island methylation signal transduction in tumors. In this report, we summarize the progress of our study on the role of MBD2 protein in tumor CpG island methylation signal transduction based on the results of our mid-term experimental work. Introduction: Aberrant CpG island methylation is a hallmark of many tumors and is as