嗜铬细胞瘤hadabpof成果.pdfVIP

Case1

◼Apatientwithpheochromocytoma(嗜铬

细胞瘤)hadaBPof250/150mmHg

andwasi.v.injectedphentolamine

rapidly,resultedinBPdecreasingto

65/40mmHg.

◼Whythishappened,howtodealwith

thecondition?

Classification:

•α-Rantagonists

•β-Rantagonists

•α,βantagonists.

Theirmajoreffectistooccupyeitherα,orβ

receptorsand

preventtheir

activationby

catecholaminesand

relatedagonists.

3

Beta-receptorantagonistdrugsarefirmly

establishedinthetreatment