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TomoTherapy?clinicalbenefitsandevidence
TomoTherapy?technology?clinicalbenefitBestPossibleIMRTesHelicalDelivery,BinaryCollimatorDailyMVCTImageGuidanceExcellenttreatmentplansDeliveredaccurately*DiseaseControl*LowToxicity*PatientConvenienceandComfort
TomoTherapy?technology?clinicalbenefitBestPossible3D-CRTesDirect3D-CRTDeliveryDailyMVCTImageGuidanceClinicallyappropriateplansDeliveredaccurately
ExcellenttreatmentplansImprovesonIMRTand3DCRTformostapplications:HeadNeckComplexbreastOrgan-onlyandorgan-plus-nodesprostateLungTotalmarrowirradiation(relativetoTBI)Rectal...andothers#XXXXXXX—CompanyConfidentialFiorinoetal.Simultaneousintegratedboost(SIB)fornasopharynxcancerwithhelicaltomotherapy.Aplanningstudy.StrahlentherOnkol2007;183:497-505.ODonnelletal.Earlyexperienceoftomotherapy-basedintensity-modulatedradiotherapyforbreastcancertreatment.ClinOncol(RCollRadiol)2009;21:294-301.Davidsonetal.Assessingtheroleofvolumetricmodulatedarctherapy(VMAT)relativetoIMRTandhelicaltomotherapyinthemanagementoflocalized,locallyadvanced,andpost-operativeprostatecancer.IntJRadiatOncolBiolPhys2011;80:1550-1558.Mengetal.Dosimetriccomparisonbetweenhelicaltomotherapyandintensity-modulatedradiationtherapyplansfornon-smallcelllungcancer.ChinMedJ(Engl)2011;124:1667-1671.Schultheissetal.Image-guidedtotalmarrowandtotallymphaticirradiationusinghelicaltomotherapy.IntJRadiatOncolBiolPhys2007;67:1259-1267.Engelsetal.Preoperativehelicaltomotherapyandmegavoltagecomputedtomographyforrectalcancer:impactontheirradiatedvolumeofsmallbowel.IntJRadiatOncolBiolPhys2009;74:1476-1480.
AccuratetreatmentdeliveryDailyMVCT-basedpatientsetupHelpsassureaccuratetreatmentdeliveryPublisheddatashowbenefitsforavarietyoftreatmentsAllowsreductionofmarginsPossibilityofdoseescalationLowerdosetonormal
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