泮托拉唑联合枸橼酸铋钾治疗胃溃疡的临床疗效研究1.docx

泮托拉唑联合枸橼酸铋钾治疗胃溃疡的临床疗效研究

【摘要】目的：探究泮托拉唑联合枸橼酸铋钾治疗胃溃疡的临床疗效。方法：选择2015年2月-2016年2月来我院就诊的206例胃溃疡患者为研究对象，将其分为两组，对照组使用阿莫西林+泮托拉唑治疗。以此为基础，观察组加用枸橼酸铋钾治疗，结束治疗后，对患者的治疗结果和治疗期间不良反应加以观察。结果：对照组患者治疗有效率为77.67%，观察组为93.20%。组间数据存在统计学差异，P＜0.05.对照组患者在治疗期间内有16例患者出现胃肠道反应，观察组患者4例出现胃肠道反应，经调整剂量后，恢复正常，未对治疗造成显著影响。从不良反应发生率上来看，对照组为15.53%，观察组为3.88%。组价数据存在统计学差异，P＜0.05.结论：对于胃溃疡者，以常规治疗为基础，对患者使用泮托拉唑联合枸橼酸铋钾进行治疗，可以取得满意效果。可快速缩小溃疡面积，不良反应少，疗效好，价格经济，值得进一步在临床治疗中推广使用。

【关键词】泮托拉唑；枸橼酸铋钾；胃溃疡；临床疗效

[Abstract]Objective:Toexploreclinicalefficacyofpantoprazolecombinedwithbismuthpotassiumcitrateinthetreatmentofgastriculcer.Methods:chooseFebruary2015-20162monthstoourhospitalof206casesofgastriculcerpatientsastheresearchobject,whichispidedintotwogroups,thecontrolgroupwithamoxicillin+pantoprazoleinthetreatmentof.Onthisbasis,theobservationgroupandtreatedwithbismuthpotassiumcitrate,theendoftreatment,thepatientstreatmentoutcomeandduringtreatmentadversereactionstobeobserved.Results:theeffectiverateofthecontrolgroupwas77.67%,andtheobservationgroupwas93.20%.Databetweengroupstherewassignificantdifference,P0.05.Controlgrouppatientsinthetreatmentperiodis16casesofpatientswithgastrointestinaltractreaction.Patientsintheobservationgroup4casesappearedgastrointestinalreaction,afterdoseadjustment,returntonormal,nottotreatmentcausedsignificanteffect.Fromtheincidenceofadversereactions,thecontrolgroupwas3.88%,theobservationgroupwas15.53%.Grouppricedata:therewasasignificantdifference,P0.05.Conclusion:forthepatientswithgastriculcer,withconventionaltreatmentbasedonpatientsusingpantoprazolecombinedwithcolloidalbismuthsubcitratetreatment,canobtainsatisfactoryresults.Canquicklyreducetheulcerarea,lessadversereaction,goodeffect,thepriceoftheeconomy,itisworthfurtherinclinicaltreatmentto