7030B-C5-生命科学试剂-MCE.pdf

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7030B-C5

Cat.No.:HY-161939

CASNo.:370871-42-4

分⼦式:C₁₇H₂₁N₅O₄

分⼦量:359.38

作⽤靶点:PCSK9

作⽤通路:MetabolicEnzyme/Protease

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性7030B-C5是⼀种PCSK9抑制剂(IC50=1.61μM)。7030B-C5在体内可显著降低⾎浆胆固醇和⽢油三酯(TG)

⽔平，并延缓动脉粥样硬化进展。7030B-C5可⽤于⼼⾎管疾病的研究。

REFERENCES

[1].XuhuiBao,etal.Targetingproproteinconvertasesubtilisin/kexintype9(PCSK9):frombenchtobedside.SignalTransductionand

TargetedTherapy9.1(2024):13.

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1/1MasterofBioactiveMolecules—您⾝边的抑制剂⼤师