Aegeline-Standard-生命科学试剂-MCE.pdf

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Aegeline(Standard)

Cat.No.:HY-W042156R

CASNo.:456-12-2

分⼦式:C₁₈H₁₉NO₃

分⼦量:297.35

作⽤靶点:Fungal

作⽤通路:Anti-infection

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性Aegeline(Standard)是Aegeline的分析标准品。本产品⽤于研究及分析应⽤。Aegeline是⼀种主要⽣物碱

，模拟酵母SNARE蛋⽩Sec22p抑制酵母α-突触核蛋⽩和Bax毒性。Aegeline恢复αsyn或Bax抑制的酵母

细胞⽣长。

REFERENCES

[1].DerfA,etal.anaturalproductfromtheplantAeglemarmelos,mimicstheyeastSNAREproteinSec22pinsuppressingα-synucleinand

Baxtoxicityinyeast[publishedcorrectionappearsinBioorgMedChemLett.2019Aug15;29(16):2437-2438].BioorgMedChemLett.

2019;29(3):454‐460.

[2].NugrohoAE,etal.Effectsofaegeline,amainalkaloidofAegleMarmelosCorrealeaves,onthehistaminereleasefrommastcells.Pak

JPharmSci.2011;24(3):359‐367.

McePdfHeight

Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

Forresearchuseonly.

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