Benzamide-Standard-生命科学试剂-MCE.pdf

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Benzamide(Standard)

Cat.No.:HY-Z0283R

CASNo.:55-21-0

分⼦式:C₇H₇NO

分⼦量:121.14

作⽤靶点:EndogenousMetabolite;PARP

作⽤通路:MetabolicEnzyme/Protease;CellCycle/DNADamage;

Epigenetics

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性Benzamide(Standard)是Benzamide的分析标准品。本产品⽤于研究及分析应⽤。Benzamide

(Benzenecarboxamide)是⼀种有效的PARP抑制剂。Benzamide对⾕氨酸和methamphetamine(METH)诱

导的神经毒性均有体外保护作⽤。Benzamide能减轻METH诱导的⼩⿏多巴胺消耗，并表现出神经保护活性

，对纹状体多巴胺代谢没有急性影响，也不降低体温。

REFERENCES

[1].CosiC,etal.Benzamide,aninhibitorofpoly(ADP-ribose)polymerase,attenuatesmethamphetamine-induceddopamineneurotoxicityin

theC57B1/6Nmouse.BrainRes.1996Oct7;735(2):343-8.

McePdfHeight

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