Lenacapavir-sodium-GS-6207-sodium-生命科学试剂-MCE.pdf

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Lenacapavirsodium

Cat.No.:HY-111964A

CASNo.:2283356-12-5

Synonyms:GS-6207sodium

分⼦式:C₃₉H₃₁ClF₁₀N₇NaO₅S₂

分⼦量:990.26

作⽤靶点:HIV

作⽤通路:Anti-infection

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性Lenacapavir(GS-6207)sodium是⼀种HIV-1⾐壳抑制剂。在MT-4细胞中，Lenacapavirsodium具有抗HIV

活性，EC50为100pM，在外周⾎单个核细胞中，对23种来⾃不同亚型的HIV-1临床分离株的平均EC50为

50pM(20-160pM)。

客户使⽤本产品发表的科研⽂献

•SciAdv.2024Apr26;10(17):eadn7033.

•SciAdv.2024Mar;10(9):eadn0042.

•PLoSPathog.2023Jun2;19(6):e1011423.

•Viruses.2022May31;14(6):1202.

•OpenForumInfectDis.2024Nov29;12(1):ofae705.

Seemorecustomervalidationsonwww.MedChemE

REFERENCES

[1].SinghK,etal.GS-CACompounds:First-In-ClassHIV-1CapsidInhibitorsCoveringMultipleGrounds.FrontMicrobiol.2019Jun

20;10:1227.

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Caution:Producthasnotbeenfullyvalidatedformedicalapplications.