HQNO-Standard-生命科学试剂-MCE.pdf

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HQNO(Standard)

Cat.No.:HY-130055R

CASNo.:341-88-8

分⼦式:C₁₆H₂₁NO₂

分⼦量:259.34

作⽤靶点:MitochondrialMetabolism

作⽤通路:MetabolicEnzyme/Protease

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性HQNO(Standard)是HQNO的分析标准品。本产品⽤于研究及分析应⽤。HQNO由P.aeruginosa产⽣的，是

⼀种有效的电⼦传递链抑制剂，对complexIII的Kd值为64nM[1]。HQNO是许多物种的线粒体NDH-2的有

效抑制剂[2]。

IC50TargetNDH-2[2]

REFERENCES

[1].NJJacobs,etal.EvidenceforInvolvementoftheElectronTransportSystemataLateStepofAnaerobicMicrobialHemeSynthesis.

BiochimBiophysActa.1977Jan6;459(1):141-4.

[2].JessicaPetri,etal.StructureoftheNDH-2-HQNOInhibitedComplexProvidesMolecularInsightIntoQuinone-BindingSiteInhibitors.

BiochimBiophysActaBioenerg.2018Jul;1859(7):482-490.

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